A comprehensive phenotypic screening strategy to identify modulators of cargo translocation by the bacterial Type IVB secretion system
E. Cheng, D. Dorjsuren, S. S. Lehman, C. L. Larson, S. Titus, H. Sun, A. Zakharov, G. Rai, R. A. Heinzen, A. Simeonov, M. P. Machner
This paper identifies compounds that inhibit T4SS-mediated effector delivery in pathogens, offering potential for pathogen-specific therapeutics.
mBio · Apr 26, 2022Peer-reviewedMicrobiology