Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium
I. Ohigashi, A. White, M.-T. Yang, S. Fujimori, Y. Tanaka, A. Jacques, H. Kiyonari, Y. Matsushita, S. Turan, M. C. Kelly, G. Anderson, Y. Takahama
The paper identifies a developmental pathway where CCL21-expressing thymic epithelial cells convert into self-antigen-displaying cells, contributing to functional diversity in the thymus medulla.
bioRxiv · Oct 3, 2023 · PreprintImmunology