M. C. Kelly

Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium

The paper identifies a developmental pathway where CCL21-expressing thymic epithelial cells convert into self-antigen-displaying cells, contributing to functional diversity in the thymus medulla.

A Multi-scale, Multiomic Atlas of Human Normal and Follicular Lymphoma Lymph Nodes

This study creates a multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes to identify tumor-specific features and microenvironmental patterns associated with early relapse.

A single-cell reference atlas delineates CD4+ T cell subtype-specific adaptation during acute and chronic viral infections

This study constructs a single-cell reference atlas of CD4+ T cell states during acute and chronic viral infections, identifying six distinct transcriptional states and their dynamics.

Urine single cell RNA-sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures in immune cells and podocytes

This study uses urine single cell RNA-sequencing to identify inflammatory signatures in immune cells and podocytes in FSGS, suggesting potential for non-invasive diagnosis and biomarker discovery.

scRNA-seq analysis of colon and esophageal tumors uncovers abundant microbial reads in myeloid cells undergoing proinflammatory transcriptional alterations

The paper develops a computational pipeline to identify microbial reads in scRNA-seq data and finds that microbial reads are enriched in myeloid cells with proinflammatory transcriptional changes.