G. Anderson

Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium

The paper identifies a developmental pathway where CCL21-expressing thymic epithelial cells convert into self-antigen-displaying cells, contributing to functional diversity in the thymus medulla.

CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages

PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages, which are key infection reservoirs for Cryptococcus neoformans.

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

The paper uses combined single-cell protein and RNA profiling to identify and characterize novel subpopulations of thymic epithelial cells and their functional roles.

The exocyst complex is an essential component of the mammalian constitutive secretory pathway

This study identifies the exocyst complex as essential for constitutive secretion in mammalian cells by showing its role in carrier fusion and cargo delivery.

Quantitative Action Spectroscopy Reveals ARPE-19 Sensitivity to Long-Wave Ultraviolet Radiation at 350 nm and 380 nm

This study uses quantitative action spectroscopy to show ARPE-19 cells are sensitive to UV-A radiation at 350nm and 380nm, with greater effects at 350nm.

High-Stability Polyimide-based Flexible Electrodes with IrOx to Interface the Mouse Vagus Nerve

This paper develops flexible polyimide-based electrodes with IrOx for interfacing mouse vagus nerve, showing stable performance and efficacy in stimulating physiological responses.

A FOXN1 mutation competitively displaces wild-type FOXN1 from higher order nuclear condensates to cause immunodeficiency

This paper identifies a FOXN1 mutation that displaces wild-type FOXN1 from nuclear condensates, leading to immunodeficiency and athymia in heterozygotes.

Inferring the genetic basis of sex determination from the genome of a dioecious nightshade

The paper generates the first genome sequence of a dioecious Solanum species and identifies the genetic basis of sex determination, finding males are the heterogametic sex and sex-specific genes are involved in pectin degradation.

Critical role of WNK1 in MYC-dependent early thymocyte development

This study identifies WNK1 as essential for thymocyte development by regulating ion homeostasis and MYC expression during the transition from double negative to double positive thymocytes.

Differential Nr4a1 and Nr4a3 expression discriminates tonic from activated TCR signalling events in vivo

The paper identifies differential Nr4a1 and Nr4a3 expression as markers distinguishing tonic from activating TCR signalling in T cells.