Author

S. V. Connelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. C. Ellis· 1 shared C. Cunningham· 1 shared C. I. Oduor· 1 shared C. P. Nixon· 1 shared D. M. Sipolski· 1 shared I. Petrow· 1 shared J. A. Bailey· 1 shared J. Brzostowski· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. C. Ellis

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2 papers

Recent·Most cited

Single-cell transcriptional changes of artemisinin-sensitive K13C580 and artemisinin-resistant K13580Y Plasmodium falciparum upon dihydroartemisinin exposure

S. V. Connelly, C. Cunningham, I. Petrow, N. Rustamzade, J. Zuromski, D. M. Sipolski, C. P. Nixon, J. D. Kurtis, J. J. Juliano, J. A. Bailey, C. I. Oduor

This study uses single-cell RNA sequencing to compare transcriptional changes in artemisinin-sensitive and resistant Plasmodium falciparum strains after dihydroartemisinin exposure, identifying metabolic and protein export differences and a potential therapeutic target.

bioRxiv · Dec 6, 2023 · PreprintMicrobiology

Restructured mitochondrial-nuclear interaction in Plasmodium falciparum dormancy and persister survival after artemisinin exposure

S. V. Connelly, J. Manzella-Lapeira, Z. C. Levine, J. Brzostowski, L. Krymskaya, R. S. Rahman, A. C. Ellis, S. N. Amin, J. M. Sa, T. E. Wellems

The paper investigates mitochondrial-nuclear interactions in Plasmodium falciparum persisters after artemisinin exposure, finding altered mitochondria and metabolic states linked to dormancy and survival.

bioRxiv · Sep 28, 2020Microbiology