Author

J. Brzostowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

J. M. Sa· 2 shared J. Manzella-Lapeira· 2 shared S. N. Amin· 2 shared A. C. Ellis· 1 shared B. Traore· 1 shared C. Micchelli· 1 shared C. Percopo· 1 shared D. L. Narum· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

J. M. Sa

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3 papers

Recent·Most cited

Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in P. falciparum persister blood stages after drug treatment

C. Micchelli, C. Percopo, M. Traver, J. Brzostowski, S. N. Amin, S. T. Prigge, J. M. Sa, T. Wellems

This study examines morphological changes in apicoplasts of P. falciparum persisters after drug treatment, finding that apicoplasts become enlarged and irregularly shaped during dormancy, with variations in shape and positioning over time.

bioRxiv · Jan 3, 2024 · PreprintMicrobiology

Restructured mitochondrial-nuclear interaction in Plasmodium falciparum dormancy and persister survival after artemisinin exposure

S. V. Connelly, J. Manzella-Lapeira, Z. C. Levine, J. Brzostowski, L. Krymskaya, R. S. Rahman, A. C. Ellis, S. N. Amin, J. M. Sa, T. E. Wellems

The paper investigates mitochondrial-nuclear interactions in Plasmodium falciparum persisters after artemisinin exposure, finding altered mitochondria and metabolic states linked to dormancy and survival.

bioRxiv · Sep 28, 2020Microbiology

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody dependent cellular cytotoxicity

G. Arora, G. T. Hart, J. Manzella-Lapeira, J. Y. A. Doritchamou, D. L. Narum, M. Thomas, J. Brzostowski, S. Rajagopalan, O. K. Doumbo, B. Traore, L. Miller, S. K. Pierce, P. Duffy, P. D. Crompton, S. A. Desai, E. O. Long

The paper shows that antibodies from malaria-exposed individuals activate NK cells to lyse infected red blood cells and inhibit parasite growth via ADCC.

bioRxiv · Mar 29, 2018Immunology