Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1
S. Yunger, B. Geiger, N. Friedman, M. J. Besser, S. A. Lieber
This study shows that a synthetic immune niche with CCL21 and ICAM1 enhances TIL expansion and cytotoxicity in vitro and in vivo.
bioRxiv · Jul 7, 2022 · PreprintImmunology