GTP cycling gates CTP synthase activation
C.-J. Guo, Y.-F. Wu, S.-Y. Guo, J.-L. Lu, L. Xu, Y. Fu, X. Zhou, J. Zhong, W. Wang, Z. Zhang, J.-L. Liu
This study reveals how GTP cycling gates CTP synthase activation through three sequential checkpoints, linking GTP binding and dissociation to catalytic steps in CTP synthesis.
bioRxiv · Sep 24, 2022 · PreprintBiochemistry