Author

S.-y. Xu

New England Biolabs (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

A. Fomenkov· 2 shared D. Heiter· 2 shared E. Yigit· 1 shared George R. Feehery· 1 shared Hang Gyeong Chin· 1 shared James C. SamuelsoniD· 1 shared Julie Beaulieu· 1 shared L. Ettwiller· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

A. Fomenkov

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct structural and functional heterochromatin partitioning of lamin B1 and B2 revealed using genome-wide Nicking Enzyme Epitope targeted DNA sequencing.

Sagnik Sen, Pierre‐Olivier Estève, Raman Karthikeyan, Julie Beaulieu, Hang Gyeong Chin, George R. Feehery, Udayakumar S. Vishnu, S.-y. Xu, James C. Samuelson, Sriharsa Pradhan

The paper uses NEED-seq to show lamin B1 and B2 associate with distinct heterochromatin states and are linked to neuronal development.

Nucleic Acids Research · Dec 26, 2024Peer-reviewedGenomics

Modification-Dependent Restriction Endonuclease-based sequencing method (EcoWI-seq) maps the genome-wide landscape of phosphorothioate modification at base resolution.

W. Yang, A. Fomenkov, D. Heiter, S.-y. Xu, L. Ettwiller

The paper introduces EcoWI-seq, a method to map phosphorothioate modifications at base resolution in bacterial genomes, showing systematic usage of target sites in modified clones.

bioRxiv · May 16, 2022 · PreprintMicrobiology

Expression and Purification of BsaXI Restriction Endonuclease and Engineering New Specificity from BsaXI Specificity (S) Subunit

S.-y. Xu, S. Gidwani, D. Heiter

This paper reports the cloning, expression, and engineering of BsaXI restriction endonuclease subunits to create new specificities by modifying the S subunit.

bioRxiv · Mar 14, 2022 · PreprintMicrobiology

Expression of human ACE2 N-terminal domain, part of the receptor for SARS-CoV-2, in fusion with maltose binding protein, E. coli ribonuclease I and human RNase A

S.-y. Xu, A. Fomenkov, T.-H. Chen, E. Yigit

This paper constructs and evaluates RNase fusion proteins with the human ACE2 N-terminal domain to degrade SARS-CoV-2 RNA in vitro.

bioRxiv · Jan 31, 2021 · PreprintMicrobiology