Author

SA Misek

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Biology Disciplines

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

EM Lisabeth· 1 shared KA Gallo· 1 shared KM Appleton· 1 shared RR Neubig· 1 shared RS Lo· 1 shared SD Larsen· 1 shared TS Dexheimer· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

EM Lisabeth

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 31, 2019

Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells

SA Misek, KM Appleton, TS Dexheimer…·RR Neubig

This study identifies RhoA-mediated gene transcription as a mechanism of BRAF inhibitor resistance in melanoma, showing that targeting this pathway can re-sensitize resistant cells to vemurafenib.

DOI 10.1101/381806

humanbulk RNA-seq

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