Author

Sabika Jafri

University Health Network

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Ahmad R. IsrawiiD· 1 shared Alyssa Shi· 1 shared Carl VirtaneniD· 1 shared Dennison Trinh· 1 shared Drake R. ThrasheriD· 1 shared Harsimar Brar· 1 shared Humaiyra Patel· 1 shared Ivy PhamiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Ahmad R. IsrawiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Translational profiling reveals novel gene expression changes in the direct and indirect pathways in a mouse model of LDOPA-induced dyskinesia

Sabika Jafri, Mahdi Ghani, Natalie H. Stickle, Carl Virtanen, Lili‐Naz Hazrati, Naomi P. Visanji

The paper uses TRAP-Bac to study translational gene expression changes in direct and indirect pathways of LDOPA-induced dyskinesia in mice, identifying pathway-specific gene expression patterns.

bioRxiv · Jun 10, 2024 · PreprintNeuroscience

Parkinsons Disease Pathology is Directly Correlated to SIRT3 in Human Subjects and Animal Models: Implications for AAV.SIRT3-myc as a Disease-Modifying Therapy.

Dennison Trinh, Ahmad R. Israwi, Harsimar Brar, Jose E.A. Villafuerte, Ruella Laylo, Humaiyra Patel, Sabika Jafri, Lina Al Halabi, Shaumia Sinnathurai, Kiran Reehal, Alyssa Shi, Vayisnavei Gnanamanogaran, Natalie Garabedian, Ivy Pham, Drake R. Thrasher, , Joanne E. Nash

This paper shows SIRT3 levels decrease with age and in Parkinson's disease, and over-expression of SIRT3 reduces α-synuclein aggregation, supporting AAV.SIRT3-myc as a potential therapy.

Neurobiology of Disease · Sep 11, 2023Peer-reviewedNeuroscience