Essential role of Hepcidin in host resistance to disseminated candidiasis
Tanmay Arekar, Divya Sai Katikaneni, Sadat Kasem, Dhruv Desai, Thrisha Acharya, Augustina Cole, Nazli Khodayari, Sophie Vaulont, Bernhard Hube, Elizabeta Nemeth, Alexander Drakesmith, Michail S. Lionakis, Borna Mehrad, Yogesh M. Scindia
This study shows hepcidin deficiency increases susceptibility to Candida albicans infection by promoting fungal growth and kidney damage, and suggests hepcidin mimetics as a potential treatment.
Cell Reports · May 1, 2025Peer-reviewedMicrobiology