AHA1 regulates Aβ production via modulation of APP expression and γ-secretase assembly
Arshad Ali Noorani, Sadequl Islam, Kevin C. Catalfano, Heather Wilkins, Brian S. J. Blagg, Kun Zou, Michael S. Wolfe
This study shows that AHA1 regulates Aβ production by modulating APP expression and γ-secretase assembly, suggesting it as a therapeutic target for Alzheimer's disease.
bioRxiv · Nov 3, 2025 · PreprintNeuroscience