Author

Kevin C. Catalfano

University of Notre DameORCID 0009-0007-1916-2682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Aaliyah KhaniD· 1 shared Alan Trudeau· 1 shared Ali A. KhaniD· 1 shared Allison Rupert· 1 shared Andrew SamiD· 1 shared Arshad Ali NooraniiD· 1 shared Ashish DuvvuruiD· 1 shared Baleigh Wheeler· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Aaliyah KhanORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 3, 2025

AHA1 regulates Aβ production via modulation of APP expression and γ-secretase assembly

Arshad Ali Noorani, Sadequl Islam, Kevin C. Catalfano…·Michael S. Wolfe

This study shows that AHA1 regulates Aβ production by modulating APP expression and γ-secretase assembly, suggesting it as a therapeutic target for Alzheimer's disease.

DOI 10.1101/2025.11.03.686106

humanexperimental assay

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Molecular BiologybioRxivPreprintDec 1, 2020

Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

Joseph H. Lubin, Christine Zardecki, Elliott M. Dolan…·Stephen Kevin Burley

The paper analyzes 3D structural changes in SARS-CoV-2 proteins during the first six months of the pandemic, showing amino acid substitutions primarily affect surfaces and boundary layers.

26 citations

virusprotein structure

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