Brian S. J. Blagg

This study shows that AHA1 regulates Aβ production by modulating APP expression and γ-secretase assembly, suggesting it as a therapeutic target for Alzheimer's disease.

This study identifies mechanisms of broad drug resistance in cancer and proposes strategies to reverse it using integrated genomic and computational approaches.

This study creates age-mimetic breast cancer models to assess drug responses in young and aged microenvironments, identifying age-specific drug targets.

This paper shows that inhibiting specific spinal cord Hsp90 isoforms enhances opioid pain relief while reducing tolerance and side effects.