Arshad Ali Noorani

This study shows that cocaine promotes growth of Streptococcus parasanguinis, which leads to neuroinflammation and memory impairment in mice without bacterial translocation.

This study shows that oral Actinomyces species from cannabis users induce anxiety-like behavior in mice through mitochondrial dysfunction and reduced GABAergic signaling.

This study shows that AHA1 regulates Aβ production by modulating APP expression and γ-secretase assembly, suggesting it as a therapeutic target for Alzheimer's disease.

This study shows that Alzheimer's mutations stabilize harmful enzyme-substrate complexes in gamma-secretase, leading to synaptic loss rather than the released Aβ peptides being the primary cause.