Author

Sagid S. Osman

University of Cincinnati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Agnese Marucci· 1 shared Ahmad T. MansouriD· 1 shared Caterina BartolacciiD· 1 shared Cristina AndreaniiD· 1 shared Gina M. DeNicolaiD· 1 shared Jessica A. KilgoreiD· 1 shared Lorenzo LucianiiD· 1 shared Margherita MelegariiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Agnese Marucci

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1 paper

Recent·Most cited

Thioredoxin Reductase 1 inhibition triggers ferroptosis in KRAS-independent lung cancers

Cristina Andreani, Caterina Bartolacci, Margherita Melegari, Nicola Sargentoni, Lorenzo Luciani, Agnese Marucci, Roberta Galeazzi, Gina M. DeNicola, Jessica A. Kilgore, Noelle Sevilir Williams, Stefano Berto, Massimiliano Gaetani, Prasad Pattabhi, Sagid S. Osman, Ahmad T. Mansour, , Pier Paolo Scaglioni

The paper identifies TXNRD1 as a therapeutic target in KRAS-WT and KRASi-resistant lung cancers by showing TRXR1 inhibition induces ferroptosis through redox mechanisms.

bioRxiv · Jul 25, 2025 · PreprintCancer Biology