Microglia-specific promoter activities of human HexB gene
Sahil Shah, Lilly M. Wong, Kendra Ellis, Brittany Bondar, Sami Saribas, Julia Ting, Zhengyu Wei, Yuyang Tang, Xianwei Wang, Hong Wang, Binhua Ling, David M. Margolis, J. Víctor García, Wenhui Hu, Guochun Jiang
The paper identifies a microglia-specific promoter of the human HexB gene that can be used for AAV gene therapy targeting microglia in the CNS.
bioRxiv · Oct 28, 2021 · PreprintNeuroscience