Binhua Ling

This study identifies APOBEC3G splicing defects in nonhuman primates that lead to different viral mutation profiles compared to humans.

This study shows that TLR3 activation in human iPSC-derived microglia-containing cerebral organoids induces antiviral factors against HIV-1.

This study shows that epigenetic modulation of NLRP6 reduces necroptosis and gastrointestinal inflammation in HIV/SIV-infected rhesus macaques.

MTD is a pipeline that jointly analyzes host and meta-transcriptomes from RNA-seq data to quantify microbiome composition and correlate it with host gene expression.

The paper identifies a microglia-specific promoter of the human HexB gene that can be used for AAV gene therapy targeting microglia in the CNS.