Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut
Chenyu Li, Christopher Adamson, Allan Wee Ren Ng, Yaquan Liang, Zebin Hong, Jia Tong Loh, Siu-Kin Ng, Jeric Mun Chung Kwan, Shiliu Feng, Evan Wei Long Ng, Sajith Nair, Christiane Ruedl, Sunny Hei Wong, Kong‐Peng Lam, Yuan Qiao
The paper identifies GlcNAc-MurNAc (GM) as a TLR4 agonist derived from gut microbiota that reduces colonic inflammation in mice.
Nature Communications · Jul 1, 2025Peer-reviewedBiochemistry