Revisiting the in vivo functions of coilin in mice: Requirement for snRNA modifications and formation of novel condensates in elongating spermatids
Miyu Ichii, Yuma Ishigami, Yao Xiao, Jianhui Li, Josei Sato, Yuki Okada, Atsushi P. Kimura, Mari Mito, Shintaro Iwasaki, Yasuyuki Kurihara, Taichi Noda, Kimi Araki, Masato Ohtsuka, Saki Ohazama, Hiroshi Maita, , Shinichi Nakagawa
This study investigates the role of coilin in mice by generating coilin mutants, revealing its involvement in snRNA modifications and the formation of novel condensates in spermatids.
bioRxiv · Nov 30, 2025 · PreprintMolecular Biology