A hypothalamic circuit links hunger to mesolimbic dopamine to drive feeding
Sam Z. Bacharach, Katherine A Zappetti, Laryssa de Oliveira Coutinho, Amanda Bacherer, Joseph I Wahba, Heather M. Schneps, Zhong-Wu Liu, Marcelo O. Dietrich, Amber L. Alhadeff
The paper identifies a hypothalamic-midbrain circuit where AgRP neurons modulate mesolimbic dopamine to drive feeding behavior in response to hunger.
bioRxiv · Sep 15, 2026 · PreprintNeuroscience