A Complex Containing HNRNPA2B1 and N6-methyladenosine Modified Transcripts Mediates Actions of Toxic Tau Oligomers
Lulu Jiang, Weiwei Lin, Cheng Zhang, Mamta Verma, Julian Kwan, Emily van Vliet, Peter E.A. Ash, Anna Lourdes Cruz, Samantha Boudeau, Brandon F. Maziuk, Shuwen Lei, Jaehyup Song, Victor E. Alvarez, Rakez Kayed, Nicholas M. Kanaan, , Benjamin L. Wolozin
This paper identifies a complex involving HNRNPA2B1, N6-methyladenosine modified transcripts, and toxic tau oligomers that mediates neurodegeneration.
bioRxiv · Dec 3, 2020 · PreprintNeuroscience