GenomicsbioRxivPreprint
Quantitative profiling of intrinsic dCas9-DNA recognition reveals key determinants of guide RNA performance
Wei Zhu, Michael Tian, Yuncheng Duan…·Raluca Gordân
This study quantifies intrinsic dCas9-DNA recognition using TANGO, identifying key factors affecting gRNA performance and revealing new aspects of dCas9 specificity.
DOI 10.64898/2026.08.10.743836