Ca2+ and cAMP open differentially dilating synaptic fusion pores
Dinara Bulgari, Samantha L. Cavolo, Brigitte F. Schmidt, Katherine Buchan, Marcel P. Bruchez, David L. Deitcher, Edwin S. Levitan
The paper shows that cAMP signaling opens dilating synaptic fusion pores for releasing large proteins, while Ca2+ triggers narrower pores for smaller cargo.
Journal of Cell Science · Jun 12, 2023Peer-reviewedNeuroscience