Developmental BiologyHuman Molecular GeneticsPeer-reviewed
Human TSC2 Mutant Cells Exhibit Aberrations in Early Neurodevelopment Accompanied by Changes in the DNA Methylome
Mary‐Bronwen L. Chalkley, Lindsey N. Guerin, Tenhir Iyer…·Rebecca A. Ihrie
This study shows that TSC2 mutant cells exhibit early neurodevelopmental abnormalities and DNA methylation changes, suggesting early gene regulation disruption in TSC.
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