Author

Lindsey N. Guerin

Vanderbilt UniversityORCID 0000-0002-2070-4481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Emily C. HodgesiD· 2 shared Rebecca A. IhrieiD· 2 shared Alan J. SimmonsiD· 1 shared Annelie JohanssoniD· 1 shared Fabio PudduiD· 1 shared Jacqueline A. Yap· 1 shared Ken S. LauiD· 1 shared Kevin C. EssiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Emily C. HodgesORCID

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2 papers

Recent·Most cited

GenomicsCell ReportsPeer-reviewedMay 1, 2025

Temporally discordant chromatin accessibility and DNA demethylation define short and long-term enhancer regulation during cell fate specification

Lindsey N. Guerin, Timothy J. Scott, Jacqueline A. Yap…·Emily C. Hodges

The paper shows that chromatin accessibility and DNA demethylation occur at different times during enhancer regulation, with methylation states predicting chromatin dynamics using machine learning.

19 citationstop 3%

humanChIP-seq

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Developmental BiologyHuman Molecular GeneticsPeer-reviewedJan 22, 2025

Human TSC2 Mutant Cells Exhibit Aberrations in Early Neurodevelopment Accompanied by Changes in the DNA Methylome

Mary‐Bronwen L. Chalkley, Lindsey N. Guerin, Tenhir Iyer…·Rebecca A. Ihrie

This study shows that TSC2 mutant cells exhibit early neurodevelopmental abnormalities and DNA methylation changes, suggesting early gene regulation disruption in TSC.

7 citations

humanDNA methylation

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