Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures
Mitchell C. Krawczyk, Jillian R. Haney, Lin Pan, Christine Caneda, Rana R. Khankan, Samuel D. Reyes, Julia W. Chang, Marco Morselli, Harry V. Vinters, Anthony Wang, Inma Cobos, Michael J. Gandal, Marvin Bergsneider, Won Bae Kim, Linda M. Liau, , Ye Zhang
This study identifies transcriptomic signatures of human astrocytes across age, sex, and disease states, revealing changes in synaptic function, ionic homeostasis, and tumor microenvironment interactions.
Journal of Neuroscience · Jan 5, 2022Peer-reviewedNeuroscience