Author

Samuel D. Waksal

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Gregory A. PetskoiD· 2 shared Scott A. SmalliD· 2 shared Suvarnambiga Kannan· 2 shared Vivek M. PateliD· 2 shared Yasir H. QureshiiD· 2 shared Beth StevensiD· 1 shared Diego E. BermaniD· 1 shared Rebecca L. CoxiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Gregory A. PetskoORCID

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2 papers

Recent·Most cited

Retromer Combinatorials for Gene-Therapy Across a Spectrum of Neurological Diseases

Yasir H. Qureshi, Vivek M. Patel, Suvarnambiga Kannan, Samuel D. Waksal, Gregory A. Petsko, Scott A. Small

The paper tests combinatorial gene therapy for retromer-related neurological diseases by expressing VPS35 with VPS26 paralogs in neurons, showing synergistic effects on retromer function and Sorl1 levels.

bioRxiv · Sep 3, 2020 · PreprintNeuroscience

Retromer repletion with AAV9-VPS35 restores endosomal function in the mouse hippocampus

Yasir H. Qureshi, Diego E. Berman, Ronald L. Klein, Vivek M. Patel, Sabrina Simoes, Suvarnambiga Kannan, Rebecca L. Cox, Samuel D. Waksal, Beth Stevens, Gregory A. Petsko, Scott A. Small

This study shows that restoring VPS35 in the hippocampus of mice with chronic neuronal VPS35 depletion rescues APP cleavage and glutamate receptor levels, and reduces glial activation similar to Alzheimer's disease.

Alzheimer s & Dementia · Jul 1, 2019Peer-reviewedNeuroscience