Author

Sabrina Simoes

Columbia UniversityORCID 0000-0002-9976-2501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Beth StevensiD· 1 shared Diego E. BermaniD· 1 shared Gregory A. PetskoiD· 1 shared Rebecca L. CoxiD· 1 shared Ronald L. Klein· 1 shared Samuel D. Waksal· 1 shared Scott A. SmalliD· 1 shared Suvarnambiga Kannan· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Beth StevensORCID

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1 paper

Recent·Most cited

Retromer repletion with AAV9-VPS35 restores endosomal function in the mouse hippocampus

Yasir H. Qureshi, Diego E. Berman, Ronald L. Klein, Vivek M. Patel, Sabrina Simoes, Suvarnambiga Kannan, Rebecca L. Cox, Samuel D. Waksal, Beth Stevens, Gregory A. Petsko, Scott A. Small

This study shows that restoring VPS35 in the hippocampus of mice with chronic neuronal VPS35 depletion rescues APP cleavage and glutamate receptor levels, and reduces glial activation similar to Alzheimer's disease.

Alzheimer s & Dementia · Jul 1, 2019Peer-reviewedNeuroscience