Author

Samuel Sampson

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Gerardo Gabriel MirizioiD· 2 shared Hee‐Woong LimiD· 2 shared Makiko IwafuchiiD· 2 shared Satoshi Matsui· 2 shared Christopher Ahn· 1 shared Katie Ludwig· 1 shared Makoto TachibanaiD· 1 shared Marissa GranittoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Gerardo Gabriel MirizioORCID

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2 papers

Recent·Most cited

Collaborative binding by diverse pioneer transcription factors amplifies Polycomb repression to preserve lineage fidelity

Gerardo Gabriel Mirizio, Morgan Buckley, Katie Ludwig, Satoshi Matsui, Samuel Sampson, Hee‐Woong Lim, Makiko Iwafuchi

The paper shows that PRDM1 collaborates with pioneer TFs to enhance enhancer repression during human endoderm differentiation, preserving lineage fidelity through hyper-bivalent enhancers.

bioRxiv · Sep 11, 2026 · PreprintGenomics

MAPK/ERK signaling blocks ectopic H3K9me3 heterochromatin formation to confer mesoderm and endoderm developmental competence

Satoshi Matsui, Marissa Granitto, Samuel Sampson, Gerardo Gabriel Mirizio, Ryo Maeda, Makoto Tachibana, Christopher Ahn, Hee‐Woong Lim, Makiko Iwafuchi

The paper shows that MAPK/ERK signaling prevents H3K9me3 heterochromatin formation at lineage-specific gene loci during mesoderm and endoderm differentiation from human pluripotent stem cells.

bioRxiv · Aug 25, 2025 · PreprintDevelopmental Biology