Author

Gerardo Gabriel Mirizio

Cincinnati Children's Hospital Medical CenterORCID 0000-0003-4774-3445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Hee‐Woong LimiD· 2 shared Makiko IwafuchiiD· 2 shared Samuel Sampson· 2 shared Satoshi Matsui· 2 shared Christopher Ahn· 1 shared Katie Ludwig· 1 shared Makoto TachibanaiD· 1 shared Marissa GranittoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Hee‐Woong LimORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 11, 2026

Collaborative binding by diverse pioneer transcription factors amplifies Polycomb repression to preserve lineage fidelity

Gerardo Gabriel Mirizio, Morgan Buckley, Katie Ludwig…·Makiko Iwafuchi

The paper shows that PRDM1 collaborates with pioneer TFs to enhance enhancer repression during human endoderm differentiation, preserving lineage fidelity through hyper-bivalent enhancers.

DOI 10.64898/2026.05.19.726322

humanChIP-seq

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Developmental BiologybioRxivPreprintAug 25, 2025

MAPK/ERK signaling blocks ectopic H3K9me3 heterochromatin formation to confer mesoderm and endoderm developmental competence

Satoshi Matsui, Marissa Granitto, Samuel Sampson…·Makiko Iwafuchi

The paper shows that MAPK/ERK signaling prevents H3K9me3 heterochromatin formation at lineage-specific gene loci during mesoderm and endoderm differentiation from human pluripotent stem cells.

DOI 10.1101/2025.08.25.672203

humanDNA methylation

𝕏 PostBluesky