Epithelial-Mesenchymal Transition Induces FAM134A-mediated ER-phagy to Regulate Procollagen Secretion
Marisa Di Monaco, Özlem Şen, Gabriella Saksono, Alessandro Vascon, Jie Ying Teo, Viktoria Brunner, Christian Schellhaas, Samuel Ulrich, Iolo J. Squires, Renata Filipe Soares, Marian Péteri, Jacob E. Corn, Jin Rui Liang
The paper shows that EMT activates ER-phagy to regulate procollagen secretion, with FAM134A uniquely mediating this process through a non-canonical mechanism.
bioRxiv · Jul 21, 2026 · PreprintCell Biology