Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis
Andrea Verdugo‐Meza, Sandeep K. Gill, Artem Godovannyi, Malavika K. Adur, Jacqueline A. Barnett, Mehrbod Estaki, Jiayu Ye, Natasha Haskey, Hannah Mehain, Jessica K. Josephson, Ray Ishida, Chanel Ghesquiere, Laura M. Sly, Deanna Lynn Gibson
This paper introduces a bio-engineered probiotic with a persistence feature that improves efficacy in colitis models, showing reduced inflammation and enhanced mucosal healing.
bioRxiv · Oct 8, 2024 · PreprintMicrobiology