Sander Ruiter

Scalable microvascular networks-on-chip enable 8-week unidirectional perfusion for long-term vascular toxicity screening

This study develops a scalable microvascular network-on-chip system that supports 8-week perfusion, revealing maturation-dependent toxicity responses to drugs.

Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow

This paper presents a scalable 3D BBB model using human cells in a microfluidic platform, showing improved barrier function with co-culture of endothelial cells, astrocytes, and pericytes.