The Prolylhydroxylase PHD2 Modulates Centromere Function through the Hydroxylation of CENP-N
Sandra C Moser, Dalila Bensaddek, Brian Ortmann, Sonia Rocha, Angus I Lamond, Jason R Swedlow
This study shows PHD2 hydroxylates CENP-N, regulating its localization and interaction with CENP-L, which affects CENP-A stability at centromeres.
bioRxiv · Nov 3, 2015 · PreprintCell Biology