Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos
Yanlin Hou, Zhengwen Nie, Qi Jiang, Sergiy Velychko, Sandra Heising, Ivan Bedzhov, Guangming Wu, Kenjiro Adachi, Hans Robert Schöler
The paper identifies the role of Oct4 and Sox2 in establishing the pluripotency network in early mouse embryos through chromatin and transcriptome analysis.
eLife · Feb 27, 2025Peer-reviewedDevelopmental Biology