Author

Sandro Barissi

Institute for Research in Biomedicine

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:machine learning (classical)· 1 Research Focus:variant effect prediction· 1 Organism:yeast· 1

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Alba SalaiD· 1 shared Federica BattistiniiD· 1 shared Miłosz WieczóriD· 1 shared Modesto OrozcoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Alba SalaORCID

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1 paper

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedAug 24, 2022

DNAffinity: A MACHINE-LEARNING APPROACH TO PREDICT DNA BINDING AFFINITIES OF TRANSCRIPTION FACTORS

Sandro Barissi, Alba Sala, Miłosz Wieczór…·Modesto Orozco

DNAffinity predicts transcription factor DNA binding affinities using physics-based machine learning from molecular dynamics simulations, outperforming existing methods and extending to epigenetic variants and in vivo binding sites in yeast.

37 citations

yeastDNA methylation

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