Miłosz Wieczór

This study investigates the mechanism of ClC-5 antiporter function and how a specific deletion causes Dent's disease, showing how simulations can aid in understanding rare diseases and personalized medicine.

The paper studies two mutations in the zebrafish Kcng4b gene, showing how they affect Kv channel function and lead to distinct developmental defects in ear development.

DNAffinity predicts transcription factor DNA binding affinities using physics-based machine learning from molecular dynamics simulations, outperforming existing methods and extending to epigenetic variants and in vivo binding sites in yeast.

The paper investigates the structural and functional impact of the S:A222V mutation in SARS-CoV-2, showing increased RBD opening and ACE2 binding without reducing neutralization capacity.