Federica Battistini

The paper reveals the structural basis of hDicer-tRNA complex formation and shows that m5C modification facilitates tRNA cleavage by hDicer.

The paper identifies 1,400 stop codon readthrough genes in Drosophila, reveals sequence features associated with programmed readthrough, and shows conserved cis-elements functional in mammalian cells.

The paper analyzes RNA backbone conformations using pseudo-torsional angles, showing that combining data from different sources provides a more complete picture and that protein interactions alter the {eta}-{theta} space.

DNAffinity predicts transcription factor DNA binding affinities using physics-based machine learning from molecular dynamics simulations, outperforming existing methods and extending to epigenetic variants and in vivo binding sites in yeast.