Transcript-specific induction of stop codon readthrough using CRISPR-dCas13 system
Lekha E. Manjunath, Anumeha Singh, Sangeetha Devi Kumar, Kirtana Vasu, Debaleena Kar, Sellamuthu Karthi, Sandeep M. Eswarappa
This paper describes a CRISPR-dCas13 system to induce stop codon readthrough in specific transcripts, showing enhanced readthrough in AGO1, VEGFA, and HBB mRNAs.
EMBO Reports · Mar 18, 2024Peer-reviewedMolecular Biology