Author

Sellamuthu Karthi

The University of Texas Medical Branch at GalvestonORCID 0000-0002-5703-9462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Anumeha SinghiD· 1 shared Debaleena Kar· 1 shared Jung Hoon YooniD· 1 shared Kirtana Vasu· 1 shared Lekha E. Manjunath· 1 shared Louise PrakashiD· 1 shared Sandeep M. EswarappaiD· 1 shared Sangeetha Devi Kumar· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperMolecular Biology

Anumeha SinghORCID

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2 papers

Recent·Most cited

WRN and WRNIP1 ATPases impose high fidelity on translesion synthesis by Y-family DNA polymerases

Jung Hoon Yoon, Sellamuthu Karthi, Louise Prakash, Satya Prakash

This study shows WRN and WRNIP1 ATPases enhance the fidelity of Y-family DNA polymerase translesion synthesis by preventing nucleotide misincorporations.

eLife · Sep 3, 2025Peer-reviewedGenetics

Transcript-specific induction of stop codon readthrough using CRISPR-dCas13 system

Lekha E. Manjunath, Anumeha Singh, Sangeetha Devi Kumar, Kirtana Vasu, Debaleena Kar, Sellamuthu Karthi, Sandeep M. Eswarappa

This paper describes a CRISPR-dCas13 system to induce stop codon readthrough in specific transcripts, showing enhanced readthrough in AGO1, VEGFA, and HBB mRNAs.

EMBO Reports · Mar 18, 2024Peer-reviewedMolecular Biology