Cyril Bařinka

The paper identifies HDAC6 and SSAT2 as enzymes regulating acetyllysine metabolism and protein homeostasis through opposing deacetylation and acetylation reactions.

This study identifies TTLL11 as a polyglutamylase that extends primary tubulin chains, revealing a new mechanism in the tubulin code and its interaction with other tubulin modifications.

This paper describes the design and characterization of a bispecific monocyte engager targeting PSMA for prostate cancer immunotherapy, showing effective activation of monocytes and tumor cell elimination.

TARDIS is a deep learning framework that rapidly and accurately segments membranes and filaments in electron microscopy data, enabling large-scale biophysical analysis.

This study identifies LG3BP as a binding partner of Sulf-2 in HNSCC and shows that LG3BP inhibits Sulf-2 activity, reducing HNSCC cell invasion.