Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
Sean C. Piantadosi, Lora Lee McClain, Lambertus Klei, Jiebiao Wang, Brittany L. Chamberlain, Sara A. Springer, David A. Lewis, Bernie Devlin, Susanne E. Ahmari
The paper identifies differentially expressed transcripts in OCD patients' striatum and OFC, showing enrichment for synapse-associated genes and changes in cell type fractions.
Translational Psychiatry · Mar 15, 2021Peer-reviewedNeuroscience