Author

Brittany L. Chamberlain

University of PittsburghORCID 0000-0002-3546-0125Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Sean C. PiantadosiiD· 2 shared Susanne E. AhmariiD· 2 shared Bernie DevliniD· 1 shared David A. LewisiD· 1 shared Elizabeth E. ManningiD· 1 shared James HydeiD· 1 shared Jamie L. PiersoniD· 1 shared Jiebiao WangiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Sean C. PiantadosiORCID

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2 papers

Recent·Most cited

Hyperactivity of indirect pathway-projecting spiny projection neurons drives compulsive behavior

Sean C. Piantadosi, Elizabeth E. Manning, Brittany L. Chamberlain, James Hyde, Zoe LaPalombara, Nicholas M. Bannon, Jamie L. Pierson, Vijay Mohan K Namboodiri, Susanne E. Ahmari

The paper identifies indirect pathway-projecting spiny projection neurons as a driver of compulsive behavior in a mouse model and shows that reducing their activity alleviates compulsive grooming.

Nature Communications · May 24, 2024Peer-reviewedNeuroscience

Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder

Sean C. Piantadosi, Lora Lee McClain, Lambertus Klei, Jiebiao Wang, Brittany L. Chamberlain, Sara A. Springer, David A. Lewis, Bernie Devlin, Susanne E. Ahmari

The paper identifies differentially expressed transcripts in OCD patients' striatum and OFC, showing enrichment for synapse-associated genes and changes in cell type fractions.

Translational Psychiatry · Mar 15, 2021Peer-reviewedNeuroscience