Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis
L. Durrieu, Daniel Kirrmaier, Tatjana Schneidt, Ilia Kats, Sarada S. Raghavan, Michael Knop, Timothy E. Saunders, Lars Hufnagel
The paper uses a fluorescent timer to analyze Bicoid gradient dynamics in Drosophila embryos, revealing parameters consistent with the synthesis-diffusion-degradation model.
Molecular Systems Biology · Sep 1, 2018Peer-reviewedDevelopmental Biology