Author

Sarah Applewhite

University of Missouri–Kansas City

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Shizhen WangiD· 2 shared Shuo Han· 2 shared Douglas F. CoveyiD· 1 shared Grace Wang· 1 shared Joshua Vance· 1 shared Katsumasa IrieiD· 1 shared Mingxing QianiD· 1 shared Rui Duan· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Shizhen WangORCID

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2 papers

Recent·Most cited

The structural dynamics and molecular coupling in the slow inactivation of a prokaryotic voltage-gated sodium channel

Katsumasa Irie, Shuo Han, Sarah Applewhite, Yuki K. Maeda, Joshua Vance, Shizhen Wang

This study uses smFRET to reveal conformational changes in the prokaryotic NavAb channel during slow inactivation, identifying key residues that coordinate structural transitions.

Nature Communications · Oct 3, 2026Peer-reviewedBiophysics

Regulation of the human voltage-gated proton channel by membrane sterols

Shuo Han, Rui Duan, Sarah Applewhite, Shuyi Wang, Grace Wang, Mingxing Qian, Douglas F. Covey, Xiaoqin Zou, Shizhen Wang

This study investigates how cholesterol and its analogs regulate the hHv1 proton channel by altering S4 segment conformation, identifying key residues and mechanisms involved.

bioRxiv · Aug 22, 2026 · PreprintBiophysics