Shizhen Wang

This study determines the activation pathway of the human voltage-gated proton channel hHV1 using computational methods, revealing voltage-driven structural changes and lipid effects validated by experiments.

This study uses smFRET to reveal conformational changes in the prokaryotic NavAb channel during slow inactivation, identifying key residues that coordinate structural transitions.

This study investigates how cholesterol and its analogs regulate the hHv1 proton channel by altering S4 segment conformation, identifying key residues and mechanisms involved.