Azacitidine Response in Myelodysplastic Syndromes is Marked by NK-like CD8 T-Cell Expansion and CXCL12+ Reticular Cell Remodeling
Henry R. Hampton, Anne Pan, Michael J. Carnell, Bofei Wang, Diana Shinko, Maria A. Kasherman, Iveta Šlapetová, Swapna Joshi, Mary N.T. Nguyen, Feng Yan, Sarah Davidson, Nick F.Y. Choi, Jason W.H. Wong, Nicodemus T. Tedla, Devendra Hiwase, , John E. Pimanda
The paper identifies NK-like CD8 T-cell expansion and CXCL12+ reticular cell remodeling as markers of azacitidine response in MDS through longitudinal bone marrow profiling.
bioRxiv · Jul 8, 2026 · PreprintCancer Biology