Author

Henry R. Hampton

UNSW SydneyORCID 0000-0002-1121-8764Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Christopher J. JollyiD· 3 shared Feng YaniD· 3 shared John E. PimandaiD· 3 shared Julie A.I. ThomsiD· 3 shared Mary N.T. NguyeniD· 3 shared Fabio ZaniniiD· 2 shared Fatemeh VafaeeiD· 2 shared Forrest C. KochiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Christopher J. JollyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms

Golam Sarower Bhuyan, Feng Yan, Mary N.T. Nguyen, Hoi Man Chung, Xiaoheng Zou, Veena Gullapalli, Lachlin Vaughan, Olivia J. Stonehouse, Henry R. Hampton, Shen Sylvie, Peter Truong, Ruchira Kumari DİSSANAYAKE, Elaheh Sadat Ghodousi, Swapna Joshi, Forrest C. Koch, , John E. Pimanda

The paper identifies cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms, showing distinct differentiation and transcriptional changes in cycling progenitors and quiescent stem cells.

bioRxiv · Jul 20, 2026 · PreprintCancer Biology

Azacitidine Response in Myelodysplastic Syndromes is Marked by NK-like CD8 T-Cell Expansion and CXCL12+ Reticular Cell Remodeling

Henry R. Hampton, Anne Pan, Michael J. Carnell, Bofei Wang, Diana Shinko, Maria A. Kasherman, Iveta Šlapetová, Swapna Joshi, Mary N.T. Nguyen, Feng Yan, Sarah Davidson, Nick F.Y. Choi, Jason W.H. Wong, Nicodemus T. Tedla, Devendra Hiwase, , John E. Pimanda

The paper identifies NK-like CD8 T-cell expansion and CXCL12+ reticular cell remodeling as markers of azacitidine response in MDS through longitudinal bone marrow profiling.

bioRxiv · Jul 8, 2026 · PreprintCancer Biology

Single cell multiomics reveal clonal and functional dynamics of MDS stem/progenitor cells during hypomethylating therapy

Julie A.I. Thoms, Henry R. Hampton, Priscilla Li Shan Boon, Olivia J. Stonehouse, Xiaoheng Zou, Hoi Man Chung, Forrest C. Koch, Feng Yan, Swapna Mahurkar Joshi, Mary N.T. Nguyen, Dorothy Hung, Dale Cameron Wright, Fatemeh Vafaee, Mark Niccolo Polizzotto, Alexander Swarbrick, , John E. Pimanda

This study uses single-cell multiomics to show that AZA response in MDS involves hematopoietic regeneration from mutated HSPCs and that AZA-refractive sub-populations contribute to disease progression.

bioRxiv · Mar 13, 2026 · PreprintCancer Biology

Multiomics Reveals Compartmentalized Immune Responses and Tissue-Vascular Signatures in Lyme Disease

Clifford Rostomily, Ameek Bhalla, Henry R. Hampton, Lance T. Pflieger, Mary E. Brunkow, Denise Cooper, Christopher G. Lausted, Ajay Suresh Akhade, Brett Smith, Kelsey Scherler, Pamela Troisch, Kai Wang, Gary P. Wormser, Noa Rappaport, Leroy Hood, Naeha Subramanian

This study uses multiomic analysis to identify compartmentalized immune responses and tissue-vascular signatures in Lyme disease, linking local immune processes to systemic symptoms.

bioRxiv · May 27, 2025 · PreprintImmunology